Only one in three small digital firms consider Europe to be a key market, said the online sales site.
A survey of more than 400 owners of small businesses with an eBay account showed that nine out of 10 sold goods or services overseas, exporting to an average of 20 different countries.
Kit Glover of eBay said: "More small online businesses are expanding into new markets with increasing vigour and we're seeing growing numbers of micro-multinational businesses emerging.
"These are agile businesses capable of selling to a global audience, without the infrastructure of a traditional exporter.
"This creates a domino effect of job creation across different sectors, from manufacturing and services to procure more products, to logistics and delivery firms shipping more goods. This is good news for small business, and good news for Britain."