The route, hailed as a game changer for the North East upon its arrival in 2007, carried 22,745 passengers in August from Newcastle and its Dubai hub.
Nick Jones, interim chief executive at Newcastle International Airport, said: “We are delighted to announce these record figures. The key to the success of Emirates is that it connects the North East to Dubai and then via Dubai to over 150 destinations.
“The Airline takes great pride in the role it plays in the region and this service has highlighted the impact a single long haul scheduled service can have.
“Next year we will celebrate 10 years of Emirates flying out of Newcastle and look forward to continuing our fantastic relationship well into the future.“
Laurie Berryman, Emirates vice president, UK, said: “Emirates began operating out of Newcastle in 2007 and since then we have seen travel from the region to Dubai and beyond flourish.
“Newcastle International Airport has become an important gateway for both business and leisure travellers in the North East, and plays an important part in the growth of the local economy.
“Like the airport, August was a very strong month for our Newcastle operation, recording a five percent annual growth. We look forward to continuing our very successful relationship long into the future.”
The Emirates service carries the vast majority of exports flown out of Newcastle Airport, the value of which now stands at £310m per annum. Before Emirates arrived in the region, flown exports stood at less than £20m.