The funding will be used over a five-year period and forms part of City’s strategy to become a leading global academic institution.
It will fund staffing as well as new programmes, information technology and ongoing estate improvements.
Prof Sir Paul Curran, president of City, University of London, said: “Securing this funding from HSBC is major step forward for City’s growth.
“With the planned programme of investment we will look to continue the successful development of our research and education capabilities, as well as our international profile.
“The lending facility means we can launch our 10-year development programme to ensure our facilities are of the highest standard, enabling us to offer the very best student and staff experience.”
On 1 September, City joined the University of London. The merger saw its name change to ‘City, University of London’.