A number of new businesses have invested in the business park during 2015, including D&S Services, Icarus and Encore Envelopes.
Companies on the park have expanded their workforces by around 600 collectively, with a further 200 jobs planned during 2016 and 2017.
Joanne Urquhart-Arnold from Business Durham sits on the Peterlee Business Park steering group which drives forward development for the East Durham area.
She said: “There's a real positive vibe among the business community which is reflected in the many positive announcements from a number of employers during 2015, who are expanding and creating jobs.
"The encouraging thing is that growth is evident in a number of sectors, from manufacturing to pharmaceuticals, and it's great to see the area doing so well.
“The steering group members, together with businesses, have worked incredibly hard to change perceptions of the area and raise its profile for the right reasons.
“Now I think there's an acknowledgement that it's not all doom and gloom here, that our businesses are growing and in the process creating jobs, bringing a huge boost to the area and its community.”
Companies including TRW, The AMA Group, Albany Assistance, Peterlee Glass and Bristol Laboratories have all outlined their intention to expand, bringing a much needed jobs-boost to the area.