Restaurant Brands International has formed a master franchise joint venture with an investor, which it hasn't named, to open Tim Hortons coffee stores across England, Scotland and Wales.
The move into Europe comes after the brand, which has outlets in Canada, the US and the Middle East, said last month that it would enter Asia by opening its first outlet in the Philippines.
Restaurant Brands, which also owns the Burger King chain of restaurants, did not say when it would open its stores in the region or how many stores it planned to open.
Restaurant Brands chief executive Daniel Schwartz said: "This deal is part of our growth plan to take the iconic Tim Hortons brand around the world.
"Great Britain is an attractive QSR (quick service restaurant) market with a strong and growing coffee culture so it is a natural fit for the brand."
Tim Hortons was founded in Canada in 1964 with a menu that includes premium coffee, speciality drinks, fresh baked goods, sandwiches and wraps.
It is particularly known for its Iced Capp, a blended coffee drink, and its Timbits doughnut bites that come in a range of flavours, such as honey dip and apple fritter.
Restaurant Brands International has more than 19,000 restaurants in almost 100 countries.
The announcement gained considerable interest on Twitter, where Luke Spillane posted: "omg holy timbits THIS IS NOT A DRILL Tim Hortons is coming to the UK!!!," while Estee Lalonde tweeted: "I will cry if this is true."